Anti-Inflammatory and Anti-Microbial Activities of Irsa (Iris ensata): A Clinical Study on the Patients of Iltehabe Unqur-Rehm (Cervicitis)

Background and Objectives: Iltehabe Unqur Rehm (cervicitis) refers to the inflammation of the cervix which may be acute or chronic causing various complications. Hence it has been decided to conduct a clinical trial for its management with Irsa. Method: Irsa was given in the form of majoon, 10 gm in two divided doses after menses for 15 days for three cycles. Extract of Irsa (10ml) was prepared and used locally in the form of humool (pessary) OD after menses for 15 days for three cycles. All the patients were assessed by subjective parameters and per speculum examination once in fifteen days for three cycles. Results: Low backache was relieved in 16 (53.3%) patients, lower abdominal pain was relieved in 21 (72.4%) patients and dyspareunia was relieved in 12 (85.7%). After the completion of the treatment 9 (100%) patients had shown improvement in abnormal vaginal odour. Relief in pruritis vulvae was observed in 20 (80%) patients. Dysuria was relieved in 19 (86.4%) patients. All the patients i.e. 30 (100%) complained of vaginal discharges. After the completion of treatment 13 (43.3%) recovered completely and on per speculum examination 30 (100%) patients had cervical discharge at the beginning of trial. After the completion of treatment 15 (50%) had shown improvement. Cervical swab culture was positive in 5 (16.7%) patients at the beginning of trial. After the completion of treatment 4 (80%) patients had shown improvement. Interpretation and Conclusion: The study revealed that the test drug is effective. So, the trial drug can be recommended to manage it. 1 Salma Mirza, 2 S.A.Naaz, 3 S.M.Alim and * 4 Azizur Rahman 1 Deptt. Niswan-o-Atfal, JTD, Deoband, District Saharanpur, India. 2 Deptt. Amraz-e-Niswan wa Atfal, AKTC, AMU, Aligarh, India 3 Unani Medical Officer, Bharatpur Govt. of Rajasthan, India. 4 PG Scholar Deptt. Of Kulliyat Umoor-e-Tabiya, NIUM Bangalore, India. Submission: 28 June 2015 Accepted: 3 July 2015 Published: 25 July 2015 www.ijppr.humanjournals.com Citation: Azizur Rahman et al. Ijppr.Human, 2015; Vol. 3 (4): 66-72. 67 INTRODUCTION In Greek Iris has two meanings “the goddess Iris” and “the Rainbow” [1]. The flowers of Irsa are yellow, dark yellow, white or sky blue in colour and due to these colour variations the drug was given the name of Irsa which means rainbow [2,3,4]. Commonly known as Sosan few says it is “Jungli sosan asmani” and few „Pahadi sosan asmani” 3 . The pulp of the root is yellowish red or white. It smells like banafsha hence named bekh-ebanafsha. Dioscoridos and Saad firastus have described about the drug. The best quality is small broad and thick which is difficult to break. The root is hard and fibrous. The odour is pungent and the taste is slightly bitter and aromatic [3,4,5].